Placenta occupies a unique position among the
endocrine glands and play a major role in endocrinology of pregnancy. The
placenta has been recognized as a source of various biological active peptides
which play important role in maintainace of pregnancy and in maternal
homeostasis during pregnancy.
The word placenta comes from the Latin for cake,
from Greek “flat, slab-like” in
reference to its round, flat appearance in humans
The placenta is an organ that attached to the lining
of mother’s womb during pregnancy that
connects the developing fetus to the uterine wall to allow nutrient uptake,
waste elimination,
The placenta is linked to baby by the umbilical
cord. Unborn fetus is inside a bag of fluid called the amniotic sac, which is
made of membranes. Now what is umbilical
cord and amniotic sac?
What is the amniotic sac?
The amniotic sac is a bag of fluid inside a woman’s
womb (uterus) where the unborn baby develops and grows. It’s sometimes called
the ‘membranes’, because the sac is made of two membranes called the amnion and
thechorion.
Umbilical cord:
In placental mammals, the umbilical cord (also
called the birth cord or funiculus umbilicalis) is the connecting cord from the
developing fetus to the placenta. During
prenatal development, the umbilical cord is physiologically and genetically
part of the fetus and (in humans) normally contains two arteries (the umbilical
arteries) and one vein (the umbilical vein. The umbilical vein supplies the
fetus with oxygenated, nutrient-richblood from the placenta. Conversely, the
fetal heart pumps deoxygenated, nutrient-depleted blood through the umbilical
arteries back to the placenta.
Steps during Synthesis of placenta:
Ø
Trophoblast: The outermost layer of cells of the blastocyst that
attaches the fertilized ovum to the uterine wall and serves as a nutritive
pathway for the embryo. Also calledtrophoderm.
Ø If a sperm
penetrates the egg, fertilization results. Tiny hairlike cilia lining the
fallopian tube propel the fertilized egg (zygote) through the tube toward the
uterus. The cells of the zygote divide repeatedly as the zygote moves down the
fallopian tube. The zygote enters the uterus in 3 to 5 days.
Ø In the
uterus, the cells continue to divide, becoming a hollow ball of cells called
ablastocyst. If fertilization does not occur, the egg degenerates and passes through
the uterus with the next menstrual period.
Ø But if egg
is fertilized then Between 5 and 8 days after fertilization, the blastocyst
attaches to the lining of the uterus, usually near the top. This process,
called implantation, is completed by day 9 or 10.
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