1- Pharmaceutical phase:
It concern with the administration route selection and preparation of most appropriate pharmaceutical formulation.
Objectives:
Optimize the distribution and facilitate to the absorption and elimination of unwanted organoleptic properties.
2- Pharmacokinetic phase:
It concern with the fate of drug in the organism its mean absorption, distribution, metabolism and excretion.
Objectives:
Control the bio-availability its means the ratio of administered dose over the concentration at site of action in function of time.
3- Pharmacodynamic Phase:
It concern with the drug receptor interaction and nature and intensity of pharmacological response.
Objectives:
Maximal activity, maximal selectivity and minimal toxicity.
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